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UFE vs. UAE: What’s the Difference?

A doctor performing an ultrasound on a woman with uterine fibroids.

When you’re dealing with symptomatic fibroids, it’s completely natural to feel overwhelmed by treatment options. The last thing you want is to feel unsure about what’s best for you, especially when it comes to procedures that impact your health, comfort, and peace of mind. 

We understand—uterine fibroids can disrupt your life in countless ways, making it essential to find a minimally invasive solution that works. Fortunately, innovative treatments like Uterine Fibroid Embolization (UFE) and Uterine Artery Embolization (UAE) offer hope. However, it can be confusing to differentiate between the two and determine which is best for treating uterine fibroids.

So in this post, the experts here at VIP Fibroid Center will break down Uterine Fibroid Embolization and Uterine Artery Embolization—including what they involve, how they’re different, and why knowing these differences matters—so you can have a clearer sense of these procedures and what you can expect from each. That way, you can make an empowered, informed decision for your uterine health.

The Definition of UFE and UAE

While Uterine Fibroid Embolization and Uterine Artery Embolization might sound similar, their unique aspects set them apart in treating fibroids effectively and safely. Understanding exactly what they are is a great starting point to feel more confident in your options.

What is UAE?

Uterine Artery Embolization (UAE) is a minimally invasive procedure that blocks blood flow to specific uterus areas by targeting uterine arteries. During the procedure, an interventional radiologist uses a tiny catheter to deliver embolic agents—small particles designed to block blood vessels—to the uterine arteries, effectively decreasing blood supply to the target area. This lack of blood flow causes the affected tissues to shrink over time, relieving symptoms without invasive surgery.

Uterine Artery Embolization is not solely reserved for treating fibroids; in fact, Uterine Artery Embolization can address a range of uterine issues, including adenomyosis (when uterine tissue grows into the uterus’ muscular wall) and postpartum hemorrhage.

Its versatility in addressing various uterine conditions beyond uterine fibroids sets UAE apart, making it a broader approach to managing uterine health. In short, Uterine Artery Embolization is the general term for any embolization procedure involving the uterine artery.

What is UFE?

On the other hand, Uterine Fibroid Embolization (UFE) is a specific type of Uterine Artery Embolization designed exclusively to treat uterine fibroids. From a technical perspective the procedures are very similar. Uterine Artery Embolization, an interventional radiologist performs Uterine Fibroid Embolization by using a catheter to introduce embolic agents that restrict blood flow. However, the difference lies in its precise focus. 

Uterine Fibroid Embolization is designed to target the uterine arteries that supply blood to the fibroids, not the entire uterine artery network. This targeted approach directly impacts fibroid tissues, causing them to shrink while preserving surrounding healthy tissues. Therefore, UFE is a powerful option for women seeking symptom relief without affecting the rest of the uterus.

Their Similarities and Differences: A Quick Overview

While Uterine Fibroid Embolization and Uterine Artery Embolization have distinct purposes, these two minimally invasive procedures share several key features, including:

  • A minimally invasive procedure requiring only a small incision
  • Outpatient treatment that allows patients to go home the same day
  • Usage of embolic agents to decrease blood flow
  • Avoidance of general anesthesia
  • Reduced recovery time compared to traditional surgery

Despite their similarities, Uterine Fibroid Embolization and Uterine Artery Embolization differ in their focus and application. Here’s what sets them apart:

  • Application: UFE is specifically for uterine fibroids while UAE is used for various uterine conditions.
  • Procedure scope: UFE targets the uterine arteries supplying fibroids while UAE can block blood flow in the broader uterine arteries depending on the condition

A Deeper Comparison of UFE and UAE

Understanding the terminology of Uterine Fibroid Embolization and Uterine Artery Embolization can be empowering, especially when deciding which treatment best suits your needs. Let’s explore some of the finer details of what makes these minimally invasive procedures both alike, and how these factors may influence your path toward relief.

Procedure Techniques

Uterine Artery Embolization is performed by an interventional radiologist using a minimally invasive technique involving a tiny incision, usually in the wrist or groin. They go through this small opening to guide a catheter to the uterine arteries, where it releases embolic agents. For conditions beyond fibroids, the radiologist may target multiple arteries to effectively reduce blood supply to the problematic tissues.

While similar in technique, Uterine Fibroid Embolization focuses specifically on fibroid-bearing uterine arteries. During UFE, the interventional radiologist uses real-time imaging to locate the arteries feeding into the fibroids and inserts the embolic agents into these targeted vessels alone.

Embolic Agents Used

In Uterine Artery Embolization, embolic agents are selected based on the condition being treated. Since this minimally invasive procedure can address various uterine issues, the size and type of particles may differ depending on the tissue targeted and how much blood flow restriction is needed. Embolic agents used for Uterine Artery Embolization typically react when they touch blood to form a solid material that blocks blood flow.

Conversely, the embolic agents used for Uterine Fibroid Embolization are typically smaller than those used for Uterine Artery Embolization since they are specifically suited to fibroids, balancing effectiveness with the preservation of surrounding tissues. These agents are carefully sized and work by closing or blocking the blood vessel’s interior space, known as the lumen.

A doctor explaining uterine fibroid treatment to a patient.

Outcome Comparisons

Uterine Artery Embolization outcomes can vary depending on the condition being treated and the extent of tissue affected. While it can bring relief for a variety of conditions that cause vaginal bleeding and pelvic pain, it may take longer for patients to see the full results since it addresses a wider area of the uterus. Its less targeted approach may also impact non-targeted tissues in the uterus depending on the procedure’s scope.

Uterine Fibroid Embolization tends to yield high success rates for uterine fibroid symptom relief. Since Uterine Fibroid Embolization directly targets the arteries feeding the fibroids, patients often experience significant improvement in symptoms such as heavy menstrual bleeding, pelvic pain, and bloating within just a few months. This minimally invasive procedure keeps the surrounding uterine tissue intact, which can lead to a faster recovery and fewer intended effects.

Terminology Usage in Medical Literature

In medical literature, Uterine Artery Embolization is often discussed as a versatile technique that applies to various uterine conditions. When searching through studies or articles, you’ll find Uterine Artery Embolization referenced in the context of treating issues like adenomyosis, postpartum hemorrhage, and other generalized uterine bleeding problems. Because of its broad application, it may be referenced as a comprehensive solution for managing heavy menstrual bleeding, pelvic pain, or other symptoms tied to uterine blood flow.

Uterine Fibroid Embolization, however, is a term you’ll find used specifically in research related to uterine fibroids. Medical studies and articles that discuss UFE generally focus on its effectiveness in treating fibroid-related symptoms and its benefits over more invasive surgical options. This precise terminology helps differentiate Uterine Fibroid Embolization as a treatment with a unique focus.

Finding Relief with VIP Fibroid Center

Choosing the right treatment for uterine fibroids can feel overwhelming, but understanding the unique benefits of Uterine Fibroid Embolization (UFE) and Uterine Artery Embolization (UAE) is a powerful step toward taking control of your health. Both treatments offer effective, minimally invasive options to restore your comfort and quality of life, and if you’re looking for relief from uterine fibroid symptoms, UFE can make all the difference.

You don’t have to navigate these decisions alone. At VIP Fibroid Center, we’re here to help you every step of the way. Our compassionate team understands the challenges of living with uterine fibroids and is dedicated to delivering advanced, patient-focused care that prioritizes your unique health goals. With our state-of-the-art, minimally invasive procedures and commitment to patient comfort, we offer the support, experience, and expertise you deserve for a seamless, stress-free journey toward relief.

Ready to explore the best options for your fibroid treatment? Request your consultation or contact our staff today and let us help you discover a path to a healthier, more comfortable future—without the need for invasive surgery. Your journey to relief and renewed wellness starts with VIP Fibroid Center.